11,045 research outputs found
The effect of competition on the control of invading plant pathogens
1. New invading pathogen strains must compete with endemic pathogen strains to emerge and spread. As disease control measures are often non-specific, i.e. they do not distinguish between strains, applying control not only affects the invading pathogen strain but the endemic as well. We hypothesise that the control of the invasive strain could be compromised due to the non-specific nature of the control.
2. A spatially-explicit model, describing the East African cassava mosaic virus-Uganda strain (EACMV-UG) outbreak, is used to evaluate methods of controlling both disease incidence and spread of invading pathogen strains in pathosystems with and without an endemic pathogen strain present.
3. We find that while many newly introduced or intensified control measures (such as resistant cultivars or roguing) decrease the expected incidence, they have the unintended consequence of increasing, or at least not reducing, the speed with which the invasive pathogen spreads geographically. We identify which controls cause this effect and methods in which these controls may be applied to prevent it.
4. We found that the spatial spread of the invading strain is chiefly governed by the incidence at the wave front. Control can therefore be applied, or intensified, once the wave front has passed without increasing the pathogenâs rate of spread.
5. When trade of planting material occurs, it is possible that the planting material is already infected. The only forms of control in this study that reduces the speed of geographic spread, regardless of the presence of an endemic strain, are those that reduce the amount of trade and the distance over which trade takes place.
6. Synthesis and applications. Imposing trade restrictions before the epidemic has reached a given area and increasing other control methods only once the wave front has passed is the most effective way of both slowing down spread and controlling incidence when the presence of an endemic strain is unknow
Coerced Mechanical Coarsening of Nanoparticle Assemblies
Coarsening is a ubiquitous phenomenon [1-3] that underpins countless processes in nature, including epitaxial growth [1,3,4], the phase separation of alloys, polymers and binary fluids [2], the growth of bubbles in foams5, and pattern formation in biomembranes6. Here we show, in the first real-time experimental study of the evolution of an adsorbed colloidal nanoparticle array, that tapping-mode atomic force microscopy (TM-AFM) can drive the coarsening of Au nanoparticle assemblies on silicon surfaces. Although the growth exponent has a strong dependence on the initial sample morphology, our observations are largely consistent with modified Ostwald ripening processes [7-9]. To date, ripening processes have been exclusively considered to be thermally activated, but we show that nanoparticle assemblies can be mechanically coerced towards equilibrium, representing a new approach to directed coarsening. This strategy enables precise control over the evolution of micro- and nanostructures
Liver Transplantation for Advanced Liver Disease with Alpha-1antitrypsin Deficiency
ALPHA-1-antitrypsin deficiency associated with chronic obstructive airway disease was recognized in 1963 by Laurell and Ericksson.1 In 1969, Sharp2 described the first cases of alpha-1-antitrypsin-deficiency disease in children with cirrhosis. Since then, this inborn error has been recognized as one of the more common factors in cirrhosis of infancy and childhood,3 including âneonatal hepatitis.â4 Alpha-1-antitrypsin is a glycoprotein that accounts for a major portion of the alpha-1 globulin fraction of the serum.5 It is responsible for approximately 90 per cent of the antitrypsin activity6 of the serum, and it also inhibits several other plasma enzymes, including plasmin,7 elastase,8 collagenase,9 and. © 1980, Massachusetts Medical Society. All rights reserved
Open Access in UCL: a new paradigm for London's Global University in research support
Open Access provides an opportunity for researchers to disseminate their research globally, but it comes with challenges. This article looks at the various ways in which UCL (University College London) has addressed those challenges, by investing in Open Access activities at the university
Aeolian sans ripples: experimental study of saturated states
We report an experimental investigation of aeolian sand ripples, performed
both in a wind tunnel and on stoss slopes of dunes. Starting from a flat bed,
we can identify three regimes: appearance of an initial wavelength, coarsening
of the pattern and finally saturation of the ripples. We show that both initial
and final wavelengths, as well as the propagative speed of the ripples, are
linear functions of the wind velocity. Investigating the evolution of an
initially corrugated bed, we exhibit non-linear stable solutions for a finite
range of wavelengths, which demonstrates the existence of a saturation in
amplitude. These results contradict most of the models.Comment: 4 pages, 5 figures, submitted to Phys. Rev. Lett. Title changed,
figures corrected and simplified, more field data included, text clarifie
On character generators for simple Lie algebras
We study character generating functions (character generators) of simple Lie
algebras. The expression due to Patera and Sharp, derived from the Weyl
character formula, is first reviewed. A new general formula is then found. It
makes clear the distinct roles of ``outside'' and ``inside'' elements of the
integrity basis, and helps determine their quadratic incompatibilities. We
review, analyze and extend the results obtained by Gaskell using the Demazure
character formulas. We find that the fundamental generalized-poset graphs
underlying the character generators can be deduced from such calculations.
These graphs, introduced by Baclawski and Towber, can be simplified for the
purposes of constructing the character generator. The generating functions can
be written easily using the simplified versions, and associated Demazure
expressions. The rank-two algebras are treated in detail, but we believe our
results are indicative of those for general simple Lie algebras.Comment: 50 pages, 11 figure
Generating-function method for tensor products
This is the first of two articles devoted to a exposition of the
generating-function method for computing fusion rules in affine Lie algebras.
The present paper is entirely devoted to the study of the tensor-product
(infinite-level) limit of fusions rules.
We start by reviewing Sharp's character method. An alternative approach to
the construction of tensor-product generating functions is then presented which
overcomes most of the technical difficulties associated with the character
method. It is based on the reformulation of the problem of calculating tensor
products in terms of the solution of a set of linear and homogeneous
Diophantine equations whose elementary solutions represent ``elementary
couplings''. Grobner bases provide a tool for generating the complete set of
relations between elementary couplings and, most importantly, as an algorithm
for specifying a complete, compatible set of ``forbidden couplings''.Comment: Harvmac (b mode : 39 p) and Pictex; this is a substantially reduced
version of hep-th/9811113 (with new title); to appear in J. Math. Phy
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